Sirolimus Tablets IP

Key Benefits
- Helps prevent kidney transplant rejection
- Supports long-term immunosuppressive therapy after transplantation
- Helps reduce excessive immune-system activity
- May be used in combination with other immunosuppressive medicines
- Supports protection of the transplanted kidney from immune-mediated rejection
How It Works
Sirolimus inhibits the mammalian target of rapamycin (mTOR), a protein pathway involved in the activation and proliferation of immune cells. By suppressing T-cell activity and multiplication, it reduces the immune response that can attack a transplanted organ.
Common Side Effects
- Increased risk of infections
- Mouth ulcers
- Diarrhea
- Nausea
- Headache
- Acne or skin problems
- Increased cholesterol or triglyceride levels
- Swelling
- Reduced blood cell counts
- Delayed wound healing
Important Information
Sirolimus Tablets IP should be used only under the supervision of a qualified transplant specialist. Regular monitoring of sirolimus blood levels, kidney function, blood counts, lipid levels, and other laboratory parameters may be required. Because it suppresses the immune system, it can increase the risk of serious infections and certain cancers. Sirolimus may also affect wound healing and blood lipid levels. Inform your healthcare professional about all medicines and supplements you are taking because significant drug interactions can occur. Do not stop or change the dose without medical advice.